Prof. Dr. Hussien O. Kadi1 , Dr. Ali Alhawery2, Abdullah H. Deghmes3, Abdulkareem A. Swaid4, Alaa Rezq Al-ssudani5, Amani Ahmed Alkhiati6, Anhar A. Hajjam7,
Samah H. Al-Omari8, Mohammed M. Qaied9, Samah M. Al-Maswari10 and Yassin M. Azman11
Faculty of Medical Sciences, Department of Medical Laboratory, Yemen University, Sana;a, Yemen
Corresponding: Prof. Dr. Hussien O. Kadi, Yemen University, Sana;a, Yemen, E-mail: hussien62@yahoo.com
ABSTRACT:
Introduction: Dengue is a disease caused by an arbovirus of the genus Flavivirus and belonging to the family Flaviviridae, transmitted by the bite of Aedes aegypti or Aedes albopictus. The dengue virus is composed of a single strand of ribonucleic acid (RNA) that has an icosahedral capsid protein coat. Four main viral serotypes (DENV-1, DENV-2, DENV-3, and DENV-4) cocirculate among humans, and these are genetically related, but antigenically distinct.
Objectives: to study the patterns of hematological parameters among Dengue fever patients.
Materials and methods: by applying the cross-sectional comparative study, fifty blood samples of suspected dengue fever patients and fifty blood samples of healthy controls were collected, and submitted to the hematological (CBC ) and serological (IgM and IgG for Dengue virus) investigations.
Results: the patterns of hematological parameters among cases revealed statistically significant differences when compared with those of controls. In the other hand, IgM and IgG results revealed significant differences among cases as compared with controls.
Conclusion: Patterns of the studied hematological parameters (Hb, HCT, TWBC, Diff. lymph. count, and platelet count), IgM, and IgG revealed statistical significant differences among cases when compared with those of controls.
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